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化疗对急性淋巴细胞白血病患者肾功能影响的临床观察 被引量:4

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摘要 【目的】探讨化疗对急性淋巴细胞白血病(ALL)患者肾脏功能的影响。【方法】选择ALL患者48例,对}匕分析化疗前后肾功能指标,并与48例正常人肾功能比较。【结果】化疗后患者血尿素氮(BUN)、肌酐(cr)、尿转铁蛋白(TRF)、免疫球蛋白G(IgG)与化疗前及正常对照比较无显著性差异(P〉o05);血清胱抑素C(CysC)、尿白蛋白(Alb)、82微球蛋白(B2一MG)及尿视黄醇结合蛋白(RBP)与化疗前及正常对照比较显著升高(P〈O.05)。【结论】化疗对ALL患者的肾脏功能有一定程度的损害,且以肾小管损害为主,在化疗过程中应加强监测,长期随访观察。
作者 李惠
出处 《医学临床研究》 CAS 2013年第7期1445-1446,共2页 Journal of Clinical Research
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