大黄非蒽醌类成分的研究

Studies on Non-anthraquinones in Rheum officinale Baill

目的 :对药用大黄非蒽醌类化学成分进行研究。方法 :色谱和光谱分析法分离和鉴定化学成分。结果 :从 85 %乙醇提取物中分得 10个非蒽醌类化合物 ,鉴定了其中的 8个 ,分别为rheosmine,胡萝卜苷 ,d 儿茶素 ,6 cinnamoylisolindleyin ,白藜芦醇 4′ O β D (6″ O 没食子酰 )葡萄糖苷 ,没食子酸 ,(- )表儿茶素 3 O 没食子酸酯和D 山梨醇。结论 :rheosmine ,D 山梨醇为首次由大黄属植物中分得。

Objective:To investigate the non anthraquinones from the root and rootstock of Rheum officinale.Method:The chemical constituents were obtained from the 85% alcohol extract of the radix and rhizoma of R. officinale by column chromatography and identified by spectroscopic analysis.Result:Ten non anthraquinones were obtained,of which eight were identified by spectroscopic analysis as rheosmine,daucosterol,d catechin,6 cinnamoylisolindleyin,(-) epicatechin 3 O gallate,resveratrol 4′ O β D (6″ O galloyl) glucopyranoside,gallic acid, D sorbitol.Conclusion:Compounds rheosmine and D sorbitol were obtained from the genus Rheum for the first time.[