槟榔药理毒理研究进展

Review of pharmacological effects and toxicological information of Arecae Semen

该文综述了槟榔的主要化学组成及对神经系统、消化系统、心血管系统、泌尿系统、生殖系统的药理作用及毒理作用。槟榔对多种寄生虫都有抑制或杀灭作用,能兴奋胆碱受体,促进小鼠胃肠推进运动,抑制幽门螺旋杆菌、许兰氏黄癣菌、流感病毒。嚼食槟榔可使口腔黏膜纤维化,具有致癌致突变作用,且有生殖和神经系统毒性。中药槟榔饮片配伍使用未见有不良反应报道。

The main chemical composition of Arecae Semen has been summarized,which can bring the pharmacological action and toxicological action to the nervous system,digestive system,cardiovascular system,urinary and reproductive system.Arecae Semen has inhibition and killing effect to most parasite.It can also activate the cholinergic receptor,promote gastrointestinal propulsive motility in mice and inhibit helicobacter pylori,Xu Lang schoenleinii,influenza virus.Arecae Semen chewing results in oral mucositis fibrosis,which has not only carcinogenic mutagenic effect but also eproductive and nervous system toxicity.And Chinese medicine Yinpian use Arecae Semen of compatibility has no adverse reaction reports.