股骨病理性骨折临床分析

Clinical analysis of the pathological fracture in femur

目的研究股骨病理性骨折的病因及临床特点。方法17例股骨病理性骨折患者,全部接受手术治疗而获病理诊断,且与临床诊断相符。结果恶性肿瘤所导致的骨折12例,占70.59%,其中以肺癌和乳腺癌最多,各3例,二者共占恶性肿瘤的50%。股骨近端的骨折占65%。自发性骨折8例及多发性骨折2例,均为恶性肿瘤所致。结论股骨病理性骨折多由恶性肿瘤所致,其中肺癌和乳腺癌最常见,股骨的近端更易于发生骨折。

Objective To study the etiolgy and clinical features of pathological fracture in femur. Methods 17 cases of pathological fracture in femur,including 10 males and 7 females with average age 39.5(13～74),were all treated surgically and their pathological diagnosis were achieved,which were consistent with the clinical diagnosis.Results 12 patients (70.59%) suffered from fracture resulted from malignant tumor,of which lung cancer and breast cancer were the commonest with 3 cases respectively (50%).The fracture of proximal end accounted for 65%.8 cases of spontaneous fracture and 2 cases of multiple fracture were all malignancy sufferers.Conclusion Malignancy is the main cause of pathological fracture in femur,of which lung cancer and breast cancer are the commonest.Proximal end of femur is the most frequent part to which fracture happens.Both spontaneous and multiple fractures are resulted from malignancy.