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中药配方颗粒的质量控制方法研究进展 被引量:16

Research progress on quality control methods of Chinese medicinal granules
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摘要 中药配方颗粒是20世纪90年代中药饮片剂型改革的产物,采用现代科技手段将传统中药饮片按一定的生产工艺制成的供临床调剂使用的颗粒剂产品,具有使用方便和疗效确定的特点。综述了近年来应用薄层色谱(TLC)法、高效液相色谱(HPLC)法、红外光谱(IR)法、紫外光谱(UV)法、超高效液相色谱(UPLC)法和气相色谱-质谱(GC-MS)联用技术等控制中药配方颗粒质量的研究进展。 Chinese medicinal granules are products of the reformation of Chinese Traditional Medicine in the 1990s, with modem science and technology, according to certain production technology we make the Chinese Traditional Medicine into the granules products which are for use of clinical dispensing and which have the characteristics of easy to use and curative effect. The article expounds some of the research work of the quality control of Chinese medicinal granules in recent years, including thin-layer chromatography, high performance liquid chromatography (HPLC), infrared spectroscopy (IR), ultraviolet spectroscopy (UV), ultra-high performance liquid chromatography (UPLC), and gas chromatography - mass spectrometry technology (GC-MS); as well as gives examples to illustrate the specific application of quality control methods of Chinese medicinal granules.
出处 《药物评价研究》 CAS 2013年第4期307-310,共4页 Drug Evaluation Research
关键词 中药配方颗粒 质量控制 薄层色谱法 高效液相色谱法 超高效液相色谱法 气质联用 Chinese medicinal granule quality control TLC HPLC UPLC GC-MS
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