糖尿病酮症酸中毒159例分析

Investigation of 159 cases of diabetic ketoacidosis

目的回顾性分析糖尿病酮症酸中毒（DKA）发生急性肾功能衰竭（ARF）可能的致病因素及其防治。方法将2003年1月～2012年12月所收治的159例DKA患者，分为急性肾功能衰竭组和非急性肾功能衰竭组，比较两组的年龄、血糖、二氧化碳结合率、肌酐水平、合并严重并发症以及预后情况。结果急性肾功能衰竭组的年龄、血糖、血渗透压、二氧化碳结合率、肌酐水平均高于非肾衰竭组，P〈0．05；急性肾衰组常合并严重的并发症，P〈0．05。结论DKA患者应积极防治各种能够导致ARF的诱因。特别是老年患者。

Objective To analyze the causes and treatment of acute renal failure in diabetic ketoacidosis （DKA）. Methods 159 patients admitted to the hospital with DKA from Jan 2003 to Dec 2012 were divided into acute renal failure group and noacute renal failure group. Age, plasma glucose, osmolality, CO2CP, Scr ,the mortality and the cure rate were com- pared between two groups. Results Age, plasma glucose, osmolality, CO2CP, Scr, the mortality of acute renal failure group were higher than those of noacute renal failure group. The patients of the acute renal failure group always had severe complica- tion. Conclusion Factors led to acute renal failure in DKA should be actively managed,specifically elderly patients.