应用异种脱细胞真皮基质预防腮腺术后味觉出汗综合征

Clinical study of prevention of Frey’s syndrome following parotidectomy using heterogeneous acellular dermal matrix

目的:评估异种脱细胞真皮基质预防腮腺切除术后味觉出汗综合征的临床疗效。方法:选取腮腺切除术患者142例,抽签分为试验组(70例)和对照组(72例),采用主观症状评价和Minor试验评估2组患者术后味觉出汗综合征的发生情况。采用SPSS18.0软件包对数据进行χ2检验。结果:试验组6/70例(8.57%)、对照组17/72例(23.61%)出现味觉出汗综合征主观症状(χ2=5.91,P<0.05)。Minor试验中,试验组10/70例(14.28%)、对照组37/72例(51.39%)出现Frey综合征客观症状(χ2=22.07,P<0.01),差异显著。结论:腮腺区域切除或浅叶切除术中应用异种脱细胞真皮基质植入,可有效预防味觉出汗综合征。

PURPOSE：To evaluate the clinical effect of heterogeneous acellular dermal matrix on preventing Frey’s syndrome after parotidectomy.METHODS：One hundred and forty-two patients were randomized into two groups,patients in experimental group（70 patients） received heterogeneous acellular dermal matrix graft and while patients in control group（72 patients） didn’t receive heterogeneous acellular dermal matrix graft.The incidence of Frey’s syndrome was evaluated after operation using subjective evaluation Minor’s starch iodine test.The data was analyzed for chi-square test using SPSS18.0 software package.RESULTS：Six of 70（8.57%）in experiment group,17 of 72（23.61%） in control group had subjective symptoms of Frey’s syndrome.There was no significant difference（χ2=5.91,P ＆lt;0.05） between the two groups.By Minor’s starch iodine test,10（14.28%） cases in experimental group and 37（51.39%） cases in contro1 group had objective symptoms.The difference between the two groups was significant（χ2=22.07,P＆lt;0.01）.CONCLUSION：The application of heterogeneous acellular dermal matrix could effectively prevent Frey’s syndrome after parotidectomy.