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依赖自然杀伤细胞活化性受体的急性髓性白血病的免疫逃逸 被引量:3

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摘要 尽管采用化疗和/或造血干细胞移植,急性髓性白血病(acut emyeloid leukemia,AML)疗效及长期生存已经得到明显改善,但仍有部分原发难治或白血病再次复发,而这两项主要原因显著制约了AML整体疗效。早在1956年,Barnes等在动物体内研究中证实,有效的免疫监视反应是清除甚至根治白血病的主要机制;有力的临床实践证据来源于成功的异基因造血干细胞移植。
作者 陈瑶 赵翔宇
出处 《中华医学杂志》 CAS CSCD 北大核心 2013年第30期2407-2409,共3页 National Medical Journal of China
基金 基金项目:北京市科技新星(2008805)
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