龙珠软膏神阙贴敷与肛门纳入治疗Ⅱ度内痔等效性随机平行对照研究

Longzhu Ointment In Treatment of Internal Rectal Administration of Randomized Parallel Controlled Clinical Study

[目的]观察龙珠软膏神阙贴敷与肛门纳入治疗Ⅱ度内痔等效性。[方法]使用随机平行对照方法,将64例门诊患者按就诊顺序编号方法随机分为两组,神阙贴敷组32例龙珠软膏5g摊于3cm×3cm凡士林纱布上,贴于脐部,外盖敷料黏贴,2次/d。肛门纳入组32例龙珠软膏5g涂抹2cm×3cm凡士林纱布上,纳肛,2次/d,连续治疗4周为1疗程。观测临床症状、痔核、不良反应。连续治疗1疗程,判定疗效。[结果]经脐治疗组32例,痊愈17例,有效12例,无效3例,治愈率53.13%,总有效率90.63%;经直肠给药组,治愈24例,有效5例,无效3例,治愈率75.00%,总有效率90.63%。总有效率、痊愈率两组间无明显差异(P>0.05)。[结论]龙珠软膏神阙贴敷治疗Ⅱ度内痔与肛门纳入给药具有等效性,肛门纳入直肠给药效果更迅速,神阙贴敷经脐治疗简单方便。

[ Objective ] Observation of different routes of administration with Longzhu ointment in treating second degree hemorrhoids curative effect. [ Method ] Using randomized controlled methods, 64 cases of clinic patients according to the order number method were randomly divided into two groups, treatment group of 32 cases of transumbilical Longzhu ointment 5g booth at 3cm × 3cm Vaseline gauze, affixed to the navel, the outer cover dressing paste, 2/d, 32 cases of rectal administration group Dragon 5g 2cm × 3cm ointment smear Vaseline gauze, anus, 2 times /d, continuous treatment for 4 weeks as 1 course of treatment. Observation of clinical symptoms, adverse reaction. Continuous 1 courses of treatment, the curative effect. [ Results ] The umbilical treatment group of 32 cases, 17 cases were cured, effective 12 cases, invalid 3 cases, the cure rate was 53.13%, the total efficiency of 90.63% ; rectal administration group, 24 cases were cured, effective 5 cases, invalid 3 cases, the cure rate was 75%, the total efficiency of 90.63%. Total effective rate, the cure rate between the two groups had no significant difference （ P〉0.05 ） . [ Conclusion ] Longzhu ointment different therapeutic approach for the treatment of second degree hemorrhoids, rectal administration effect is more precise, simpleand convenient by umbilical treatment, the effective rate of not less than rectal administration.