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参麦注射液与缬沙坦联合西药治疗慢性充血性心力衰竭随机平行对照研究 被引量:4

Shenmai Injection and Valsartan combined with Western Medicine Treatment of Chronic Congestive Heart Failure Randomized Controlled Study
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摘要 [目的]观察参麦注射液与缬沙坦联合西药治疗慢性充血性心力衰竭疗效。[方法]使用随机平行对照方法,将180例住院患者按随机数字表法分为三组,对照组60例常规治疗。缬沙坦组60例缬沙坦80mg/次,1次/d,口服,常规治疗同对照组。参麦缬沙坦组60例参麦注射液25mL+5%葡萄糖注射液100mL静滴,1次/d;缬沙坦、常规治疗同缬沙坦组及对照组。连续治疗30d为1疗程。观测临床症状、心功能分级(每搏输出量-SV、心排血量-CO、射血分数-EF)、不良反应。连续治疗1疗程,判定疗效。[结果]临床疗效缬沙坦组、联合组均优于对照组(P<0.05,P<0.01),联合组优于缬沙坦组(P<0.05);心功能分级各组均有改善(P<0.05,P<0.01),缬沙坦组、联合组均优于对照组(P<0.05,P<0.01),联合组优于缬沙坦组(P<0.05);心功能指标各组均有改善(P<0.05,P<0.01),缬沙坦组、联合组均优于对照组(P<0.05,P<0.01),联合组优于缬沙坦组(P<0.05)。[结论]参麦注射液与缬沙坦联合西药治疗慢性心力衰竭,可改善心功能,提升疗效。 [ Objective ] Observed SMI valsartan combined with Western medicine treatment of chronic congestive heart failure treatment. [ Method ]Using randomized controlled method, 180 cases of hospitalized patients were randomly divided into three groups, the control group, 60 cases of conventional treatment. Valsartan Valsartan group of 60 patients 80mg / times, 1 times / day, orally, conventional treatment with the control group. Valsartan group, 60 cases SMI 25mL +5% glucose injection 100mL infusion, 1 / d; valsartan, conventional treatment with valsartan group and control group. 30d is a course of continuous treatment. Observation of clinical symptoms, cardiac function ( stroke volume-SV, cardiac output-CO, ejection fraetion-EF ), adverse reactions. Continuous treatment of a course of treatment, to determine efficacy. [ Results ] Clinical valsartan combination group than the control group ( P 〈0.05, P 〈0.01 ), the combination group than valsartan group ( P 〈0.05 ) ; cardiac function improved in each group ( P 〈0.05, P 〈0.01 ), valsartan group and combination group than the control group ( P 〈0.05, P 〈0.01 ), the combination group than valsartan group ( P 〈0.05 ) ; cardiac function in each group were improved ( P 〈0.05, P 〈0.01 ), valsartan group and combination group than the control group ( P 〈0.05, P 〈0.01 ), the combination group than valsartan group ( P 〈0.05 ) . [ Conclusion ~ SMI valsartan combined with Western medicine treatment of chronic heart failure, can improve heart function, enhance the effect.
作者 李佳 焦晓民
出处 《实用中医内科杂志》 2013年第5期65-68,共4页 Journal of Practical Traditional Chinese Internal Medicine
关键词 慢性充血性心力衰竭 心悸 参麦注射液 缬沙坦 中西医结合治疗 随机平行对照研究 Chronic congestive heart failure Palpitations Shenmai injection Valsartan IntegrativeMedicine Randomized controlled study
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