摘要
[目的]观察参麦注射液与缬沙坦联合西药治疗慢性充血性心力衰竭疗效。[方法]使用随机平行对照方法,将180例住院患者按随机数字表法分为三组,对照组60例常规治疗。缬沙坦组60例缬沙坦80mg/次,1次/d,口服,常规治疗同对照组。参麦缬沙坦组60例参麦注射液25mL+5%葡萄糖注射液100mL静滴,1次/d;缬沙坦、常规治疗同缬沙坦组及对照组。连续治疗30d为1疗程。观测临床症状、心功能分级(每搏输出量-SV、心排血量-CO、射血分数-EF)、不良反应。连续治疗1疗程,判定疗效。[结果]临床疗效缬沙坦组、联合组均优于对照组(P<0.05,P<0.01),联合组优于缬沙坦组(P<0.05);心功能分级各组均有改善(P<0.05,P<0.01),缬沙坦组、联合组均优于对照组(P<0.05,P<0.01),联合组优于缬沙坦组(P<0.05);心功能指标各组均有改善(P<0.05,P<0.01),缬沙坦组、联合组均优于对照组(P<0.05,P<0.01),联合组优于缬沙坦组(P<0.05)。[结论]参麦注射液与缬沙坦联合西药治疗慢性心力衰竭,可改善心功能,提升疗效。
[ Objective ] Observed SMI valsartan combined with Western medicine treatment of chronic congestive heart failure treatment. [ Method ]Using randomized controlled method, 180 cases of hospitalized patients were randomly divided into three groups, the control group, 60 cases of conventional treatment. Valsartan Valsartan group of 60 patients 80mg / times, 1 times / day, orally, conventional treatment with the control group. Valsartan group, 60 cases SMI 25mL +5% glucose injection 100mL infusion, 1 / d; valsartan, conventional treatment with valsartan group and control group. 30d is a course of continuous treatment. Observation of clinical symptoms, cardiac function ( stroke volume-SV, cardiac output-CO, ejection fraetion-EF ), adverse reactions. Continuous treatment of a course of treatment, to determine efficacy. [ Results ] Clinical valsartan combination group than the control group ( P 〈0.05, P 〈0.01 ), the combination group than valsartan group ( P 〈0.05 ) ; cardiac function improved in each group ( P 〈0.05, P 〈0.01 ), valsartan group and combination group than the control group ( P 〈0.05, P 〈0.01 ), the combination group than valsartan group ( P 〈0.05 ) ; cardiac function in each group were improved ( P 〈0.05, P 〈0.01 ), valsartan group and combination group than the control group ( P 〈0.05, P 〈0.01 ), the combination group than valsartan group ( P 〈0.05 ) . [ Conclusion ~ SMI valsartan combined with Western medicine treatment of chronic heart failure, can improve heart function, enhance the effect.
出处
《实用中医内科杂志》
2013年第5期65-68,共4页
Journal of Practical Traditional Chinese Internal Medicine