针刺调节慢性盆腔炎CRP、TNF-α随机平行对照研究

Regulate Acupuncture in Patients with Chronic Pelvic Inflammatory Disease CRP TNF-α Randomized Controlled Study

[目的]观察针刺调节慢性盆腔炎CRP、TNF-α疗效。[方法]使用随机平行对照方法,将90例住院患者按随机数字表法分为三组。八正散组30例:八正散(栀子、大黄、木通、瞿麦、扁蓄各9g,车前子12g,滑石15g,甘草梢6g),1剂/d,水煎300mL,早晚口服。抗生素组30例左氧氟沙星,500mg/d;甲硝唑,500mg/d,静滴。针刺组30例针刺,电仪针、针灸针1.5寸和1寸;取穴关元、气海、中极、归来、次髎、足三里、三阴交;关元、次髎用补法,余穴采用平补平泻手法;1次/d,得气后留针30min。连续治疗10d为1疗程。观测临床症状、反应蛋白(CRP)、肿瘤坏死因子-a(TNF-α)、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组治愈14例,显效11例,有效4例,无效1例,总有效率97.67%。八正散组痊愈5例,显效5例,有效12例,无效8例,总有效率73.33%。抗生素组治愈5例,显效5例,有效13例,无效1例,总有效率76.67%。针刺组疗效优于八正散组和抗生素组(P<0.05);CRP、TNF-α水平改善针刺组优于八正散组和抗生素组(P<0.05)。[结论]针刺调节慢性盆腔炎CRP、TNF-α效果显著,值得推广。

[ Objective ] To observe the effect of chronic pelvic inflammatory regulator CRP, TNF- α treatment.[ Methods ] Using randomized controlled method, 90 cases of hospitalized patients were randomly divided into three groups. Control group, eight are scattered group of 30 patients： eight are scattered （ Zhizi, Dahuang, Mutong, Qumai, Bianxu each 9g, Cheqianzi 12g, Huashi 15g, Gancaoshao 6g ）, 1 does / d, decoction 30OraL, sooner or later, oral, subtraction with the card. Antibiotic levofloxacin group of 30 patients, 50Omg / d ; metronidazole, 500mg / d, intravenously. Acupuncture treatment group, 30 patients acupuncture, electric meter needles, acupuncture needles 1.5-inch and one inch; acupoints GuanYuan, Qihai, Zhongji, Guilai, Ciliao, Zusanli, Sanyinjiao; Guan Yuan, Ciliao with fill France, I point using reinforcing-reducing techniques; 1 times / d, after the gas needle 30min. continuous treatment 10 times as a course of treatment. Observing clinical symptoms, reactive protein （ CRP ）, tumor necrosis factor-α （ TNF- α ）, adverse reactions. Continuous treatment of 3 courses, to determine efficacy. [ Results ] treatment group, 14 cases were cured, 11 cases markedly effective in 4 cases, 1 case, the total effective rate 97.67%. Control group, eight are scattered five cases were cured, 5 cases markedly effective in 12 cases, 8 cases, the total efficiency of 73.33%. Antibiotic control group were cured in 5 cases, 5 cases markedly effective in 13 cases, 1 case, the total effective rate 76.67%. Treatment group than the control group （ P 〈0.05 ） . CRP, TNF- αlevels to improve the treatment group than the control group （ P 〈0.05 ） . [ Conclusion ] acupuncture regulating chronic pelvic CRP, TNF- effect is significant, worthy of promotion.