健脾化痰活血法结合西药治疗2型糖尿病合并高脂血症疗效观察

Combination of strengthening spleen,eliminating phlegm and activating blood circulation method and western medicine for the treatment of type 2 diabetic hyperlipemia

目的观察健脾化痰活血法结合西药治疗2型糖尿病合并高脂血症的临床疗效。方法将87例患者随机分为观察组(45例)和对照组(42例)。两组均予二甲双胍肠溶片和阿托伐他汀钙片治疗,观察组同时加用健脾化痰活血中药。两组疗程均为3个月,观察临床疗效及血糖、血脂指标变化情况。结果观察组、对照组总有效率分别为95.56%、80.95%;组间临床疗效比较,差异有统计学意义(P<0.05)。两组治疗前后组内比较,血脂(TC、TG、LDL-C、HDL-C)差异均有统计学意义(P<0.05),血糖(FPG、2 hPG)差异无统计学意义(P>0.05);组间治疗后比较,TC、TG和HDL-C差异有统计学意义(P<0.05)。结论健脾化痰活血中药联合西药二甲双胍肠溶片和阿托伐他汀钙片用于治疗2型糖尿病合并高脂血症,临床疗效良好,在改善临床症状和降低血脂方面优于单纯西药。

Objective To observe the clinical efficacy of strengthening spleen, eliminating phlegm and activating blood circulation method combined with western medicine in treating type 2 diabetic hyperlipemia. Methods Eighty-seven cases were randomly divided into observation group （ 45 cases ） and control group （42 cases）. Both of the groups were treated with Diformin Tablet and Atorvastatin Calcium Tablet, and observation group was treated by Chinese medicine additionally, with the course of 3 months. The clinical efficacy, blood sugar and indicator of serum lipid were observed. Results The overall effective rate was 95.56% in the treatment group and 80.95% in the control group, with a difference between the two groups （P 〈0.05 ）. Before and after treatment, there were significant differences in blood lipid （ TC, TG, LDL-C, HDL-C ） in each group （ P 〈 0.05 ）, and no significant difference was found in blood sugar （ FPG, 2 hPG） （ P 〉 0.05 ） ; after treatment, there were significant differences in TC, TG and HDL-C between the two groups （ P 〈 0.05 ）. Conclusion Combined Chinese medicine with strengthening spleen, eliminating phlegm and activating blood circulation functions and western medicine together has positive effect on type 2 diabetic hyperlipemia. Its therapeutic effect is better than the western medicine in improving clinical symptoms and reducing blood lipid aspects.