子宫内膜息肉与不孕症相关因素分析

Correlation analysis between endometrial polyps and infertility

目的探讨子宫内膜息肉的数目、位置和大小与不孕症之间的关系。方法108例子宫内膜息肉伴不孕症患者行宫腔镜检查并行息肉切除和助孕，观察息肉个数、位置和大小和不孕之间的关系。结果输卵管开口息肉切除后的妊娠率明显高于后壁、前壁、侧壁（P〈0．01），后壁、前壁、侧壁组间差异无统计学意义（P〉0．05）。多发息肉切除后子宫妊娠率明显高于单发息肉切除后子宫妊娠率（P〈0．05）。单发性息肉中，直径〈5mm、5—10mm、11—20mm息肉切除后妊娠率差异无统计学意义（P〉0．05）。息肉直径〉20mm时妊娠率明显低于息肉直径〈20mm患者的妊娠率，差异有统计学意义（P〈0．05）。结论息肉引起不孕与息肉的数目、位置和大小有一定的联系，应行官腔镜和针对性治疗，提高妊娠率。

Objective To explore the number, size and location of the endometrial polyps of infertile women. Methods 105 infertile women with endometrial polyps had hysteroscopy, polypectomy and assisted pregnancy, the number, location and size of polyp were observed to analyze their correlation with infertility. Results Pregnancy rate of uterine after tubal opening polypectomy was significantly higher than that of uterine after polypectomy of the rear wall, anterior wall, lateral wall （P〈0.01）, and pregnancy rate of uterine after polypectomy of posterior wall, anterior wall, lateral wall had no significant difference （P〉0.05）. Pregnancy rate of uterine after multiple polyps polypectomy was significantly higher than that of uterine after single polyps polypectomy （P〈0.05）. In single polyps, pregnancy rate of patients with 〈5 mm, 5~10 mm, 11~20 mm had no significant difference （P〉0.05）. Pregnancy rate of patients with 〉20 mm was significantly lower than that of patients with 〈20 mm （P〈0.05）. Gonelusion The number, location and size of polyp can cause infertility, which should be treated with hysteroscopy and targeted therapy, and improve the pregnancy rate.