高血压性脑出血早期血肿扩大与血压指标的相关性研究

Study on correlation between early hematoma enlargement and blood pressure indexes in hypertensive intracerebral hemorrhage

目的探讨高血压性脑出血患者早期血肿扩大与血压指标的关系。方法收集179例高血压性脑出血患者,根据入院前及入院后24 h头颅计算机断层扫描(CT)的变化分为血肿扩大组24例及血肿未扩大组155例。监测入院后24 h的动态血压,记录收缩压、舒张压及血压变异指标,并分析其与血肿扩大的关系。结果血肿扩大组最大收缩压及平均收缩压显著高于血肿未扩大组。血肿扩大与收缩压最大值、收缩压值均相关。结论高血压性脑出血24 h内血肿扩大和最大收缩压、平均收缩压密切相关,舒张压对其影响不大,且与血压变异关系不大,可能与早期降压药物的应用有关。

Objective To explore the relationship between early hematoma enlargement and blood pressure indexes in patients with hypertensive intracerebral hemorrhage.Methods One hundred and seventy-nine patients with hypertensive intracerebral hemorrhage were selected.According to the changes of CT on the skull before hospitalization and 24 h after hospitalization,they were divided into hematoma enlargement group（n=24） and non-hematoma enlargement group（n=155）.The dynamic blood pressure was detected 24 h after hospitalization.Systolic pressure,diastolic pressure and indexes of blood pressure variability were recorded,and its relationship with hematoma enlargement was analyzed.Results The maximum and mean systolic pressures in hematoma enlargement group were both higher than those in non-hematoma enlargement group significantly.Hematoma enlargement was both related to maximum and mean systolic pressures.Conclusion Hematoma enlargement is closely related to maximum and mean systolic pressures within 24 h of hypertensive intracerebral hemorrhage,and it almost has no association with diastolic pressure and blood pressure variability,which may be related to early application of antihypertensive drugs.