全胸腔镜肺叶切除与开胸肺叶切除治疗非小细胞肺癌疗效对比研究

Comparative study of full thoracoscopic lobectomy with conventional thoracotomy in treatment of non-small cell lung cancer

目的比较全胸腔镜肺叶切除与开胸肺叶切除治疗非小细胞肺癌的临床疗效。方法 68例非小细胞肺癌患者根据手术方式不同分为2组,全胸腔镜肺叶切除组38例,开胸肺叶切除术组30例,观察比较2组在手术时间、术中出血量、术后引流量、术后引流管拔除时间、淋巴结清扫数、术后哌替啶使用次数、术后住院时间以及术后并发症方面的差异。结果全胸腔镜肺叶切除组的术中出血量、术后放置引流时间、引流量、哌替啶使用次数及术后住院时间明显小于开胸肺叶切除术组,差别均有统计学意义(P<0.01),而手术时间则明显高于开胸肺叶切除术组,差别也有统计学意义(P<0.01);全胸腔镜肺叶切除组的术后并发症发生率明显低于开胸肺叶切除术组,差别有统计学意义(P<0.01)。结论全胸腔镜肺叶切除术是较为安全、可靠的治疗非小细胞肺癌的方法。

Objective To explore the clinical effects of full thoracoscopic lobectomy with conventional thoracotomy in treatment of non-small cell lung cancer.Methods Sixty-eight non-small cell lung cancer patients were retrospectively analyzed and divided into two groups.Thirty-eight were treated with full thoracoscopic lobectomy and 30 were treated with conventional thoracotomy surgery.The operation duration,blood loss,chest tube drainage flow,length of chest tube drainage,harvested lymph nodes,postoperative dosage of dolantin,postoperative hospital stay,and postoperative complications of the two groups were compared.Results The blood loss,chest tube drainage flow,length of chest tube drainage,postoperative dosage of dolantin and postoperative hospital stay of the full thoracoscopic lobectomy group were significantly shorter than the conventional thoracotomy group（P〈0.01）,but the operative time was significantly higher than the conventional thoracotomy group（P〈0.01）.The postoperative complications rates of the full thoracoscopic lobectomy group was 10.53%,which was significantly lower than the conventional thoracotomy group,56.67%（P〈0.01）.Conclusion The full thoracoscopic lobectomy is safe and good surgical method for non-small cell lung cancer.