去白细胞成分输血在老年肿瘤患者输血治疗中的应用价值

Clinical application of leukocyte-depleted blood component transfusionin in elderly patients with tumor

目的探讨去白细胞悬浮红细胞悬液在老年肿瘤患者输血治疗中的临床应用价值。方法选取本院186例肿瘤患者作为研究对象,根据血液输注的不同分为去白细胞组(n=103)、悬浮红组(n=52)和对照组(n=31)。比较各组临床治疗效果。结果去白细胞组输血反应发生率为5.8%,显著低于悬浮红组的15.4%(P<0.05);去白细胞组术后感染率为11.7%,均显著低于悬浮红组的42.4%和对照组的29.2%(P<0.05);去白细胞组平均愈合天数为(11.3±2.4)d,高于悬浮红组的(13.8±2.8)d和对照组的(11.7±2.6)d(P<0.05);去白细胞组愈合率为97.1%,高于悬浮红组的86.5%(P<0.05)。结论去白细胞悬浮红细胞悬液输注治疗老年肿瘤患者安全有效,值得临床推广应用。

Objective To investigate the clinical application value of leukoreduction of red cells suspension in the treatment of elderly cancer patients.Methods One hundred and eighty-six cancer inpatients of our hospital were chosen and divided into different blood transfusions leukocyte removal group （n =103）,suspension of red blood cells （n =52）,the control group （n =31）,and clinical effects of the three groups were compared.Results Leukocyte removal group transfusion reaction incidence was 5.8 ％,which showed a significant difference to （P ＜ 0.05） a suspension of red blood cells group whose incidence was 15.4％.Postoperative infection rate was 11.7％,lower than the red cells suspension group （42.2％）,the control group （29.2％）,the difference being statistically significant （P ＜ 0.05）.Healing time on average was 1 1.3 days （11.3 ± 2.4）,higher than the suspension of red blood cells group（13.8 ± 2.8）,the control group（11.7 ± 2.6）,and the difference was statistically significant （P ＜ 0.05）.Healing rate of 97.1％,higher than the red cells suspension group （86.5 ％）,difference being statistically significant （P ＜ 0.05）.Conclusion The leukoreduction of red cells suspension transfusion in elderly cancer patients is safe,effective,and suitable for clinical promotion.