超敏C反应蛋白与血脂联合检测在心脑血管疾病诊断中的应用

Feasibility analysis of hypersensitive c reactive protein and blood lipid of joint detection in the diagnosis of heart cerebrovascular disease

目的分析超敏C反应蛋白和血脂联合检测在心脑血管疾病中的诊断可行性。方法选取2011年2月至2012年7月在我院治疗的心脑血管病患者150例为研究对象进行回顾性分析,根据患者病情分为5组,另选取同期对照组,比较6组甘油三脂(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB)、超敏C反应蛋白(hs-CRP)水平差异。结果 TG、TC、LDL-C、hs-CRP、ApoB均显著升高,与对照组比较差异有统计学意义(P<0.05);HDL-C、ApoA1明显降低,与对照组比较差异有统计学意义(P<0.05)。结论超敏C反应蛋白和血脂联合检测对于心脑血管疾病的临床诊断、治疗具有积极意义,能够评估预后。

Objective To analyze the feasibility of hypersensitive c-reactive protein and blood lipid joint detection in diagnostic of heart cerebrovascular disease.Methods A retrospective analysis was made of 150 patients with cardio-cerebrovascular disease selected from February 2011 to July 2012 in our hospital.According to patients＇ situation,they were divided into five groups,and others were selected in the control group during this period.Comparison was made between several groups in terms of triglycerides （TG）,total cholesterol （TC）,high-density lipoprotein cholesterol （HDL-C）,low density lipoprotein cholesterol （LDL-C）,apolipoprotein A1 （ApoA1）,apolipoprotein B （ApoB）,and hypersensitive c-reactive protein （hs-CRP） level.Results TG,TC,LDL-C,hs-values of the observation group significantly increased.The difference to the control group had statistical significance （P ＜ 0.05）.CRP and ApoB markedly decreased compared with the control group,the difference being statistical significant （P ＜ 0.05）.Conclusion Hypersensitive c-reactive protein and blood lipid joint detection plays a positive role in detecting heart cerebrovascular disease.It can also assess prognosis.