泮托拉唑联合奥曲肽在消化道溃疡合并出血中的临床应用

The Clinical Application of Octreotide Combined with Pantoprazole in Gastrointestinal Ulcer Bleeding

目的探讨泮托拉唑联合奥曲肽在消化道溃疡合并出血治疗中的临床作用。方法回顾分析近6年我科收治的76例消化道溃疡合并出血病例,观察组采用泮托拉唑奥曲肽治疗34例,对照组采用泮托拉唑治疗32例,对比临床症状改善情况、止血情况和溃疡愈合情况。结果泮托拉唑联合奥曲肽治疗组短期内症状改善明显、在止血时间和溃疡愈合时间上明显早于对照组,有统计学差异,治疗中未发现明显毒副反应。结论泮托拉唑联合奥曲肽在消化道溃疡合并出血治疗中效果显著。

Objective To investigate octreotide combined with pantoprazole clinical role in the treatment of peptic ulcer with bleeding. Methods 6 cases of peptic ulcer with hemorrhage cases were divided into the observation group （34 cases ） and the control group group （32 cases）. The observation group were treated with octreotide combined with pantoprazole, and the control group treated with pantoprazole treatment, compared clinical improvement of symptoms hemostatic situation and ulcer healing in past six years. Results The group of octreotide combined with pantoprazole treatment improved significantly in short time to stop bleeding and ulcer healing time significantly earlier than the control group, a significant difference, without significant toxicity in the treatment. Conclusion Octreotide with pantoprazole was significant in the treatment hemorrhage of peptic ulcer.