藻酸双酯钠对急性脑梗死患者神经功能恢复的影响

Effect of propylene glycol alginate sodium on recovery of neurological function in patients with acute cerebral infarction

目的探讨藻酸双酯钠对急性脑梗死患者神经功能恢复的影响。方法回顾性分析本院收治的72例急性脑梗死合并神经功能缺失患者的临床资料,根据治疗方法分为治疗组和对照组,每组36例。对照组患者给予曲克芦丁进行治疗,治疗组患者给予藻酸双脂钠进行治疗,比较2组患者的临床疗效,NIHSS评分和BI指数。结果治疗后,治疗组的总有效率为91.67%,显著高于对照组的83.33%(P<0.05);治疗组的基本痊愈率为47.22%,显著高于对照组的38.89%(P<0.05);治疗前,2组患者的NIHSS评分和ADL评分比较均无显著性差异。治疗后治疗组患者的NIHSS评分显著低于对照组,BI指数显著高于对照组,差异均有统计学意义(P<0.05)。结论藻酸双脂钠能明显改善急性脑梗死患者的神经功能。

Objective To observe the effect of propylene glycol alginate sodium on recovery of neurological function in patients with acute cerebral infarction. Methods A retrospective analysis was made of the clinical data of 72 patients admitted to our hospital with acute cerebral infarction patients with neurological deficits. They were divided into treatment group and control group, 36 cases in each group. The control group was treated with venoruton treatment, and the treatment group with alginic acid sodium diester treatment. The clinical effects, NIHSS score and BI index of the two groups were compared. Results After treatment, the total efficacy rate was 91.67% in the treatment group, markedly higher than the control group （83.33%, P〈0.05）. The total cure rate was 47.22 %, markedly higher than the control group （38.89 %, P 〈 0.05 ）. Before treatment, NIHSS score and ADL scores of the two groups showed no significant difference. After treatment, NIHSS score of the treatment group was markedly lower than the control group, and Blindex was remarkably higher than the control group （P 〈 0.05）. Conclusion Propylene glycol alginate sodium can significantly improve neurological function in patients with acute cerebral infarction.