肝门部胆管癌手术治疗的临床疗效观察

Observation of clinical effect of surgical Treatment on patients with hilar cholangiocarcinoma

目的探讨肝门部胆管癌(HCC)手术治疗方式及疗效。方法回顾性分析2006年1月至2008年1月本院采用不同手术方式治疗的130例HCC患者的临床资料,随机分为观察组和对照组,观察组采用根治性切除,对照组采用非根治性切除,比较2组手术方式的临床疗效。结果观察组患者的生存时间,1、3、5年的生存率明显高于对照组,2组差异有统计学意义(P<0.05);2组术后并发症差异无统计学意义(P>0.05)。结论根治性切除能够显著延长HCC患者的生存时间,减少并发症,降低死亡率。

Objective To explore the therapeutic strategies and curative effects of hilar cholangio carcinoma（HCC）. Methods A retrospective analysis was made of clinical data of 130 patients with hilar eholangio carcinoma who received different surgical treatments from Jan. 2006 to Jan. 2008. The patients were randomly divided into observation group and control group. The observation group was applied with radical resection and the control group non- radical resection. The two groups were compared in terms of clinical effect of the two difference operative methods. Results Survival rates in 1st , 3rd , 5th year of survival time the observation group were obviously higher than those of the control group, the difference between the two groups having statistical significance （P 〈 0.05）. The postoperative complications of the two groups had no significant difference （P 〉 0. 05）. Conclusion Radical resection can markedly prolong the survival time of HCC patients, and reduce the complications and mortality.