丹红注射液联合辛伐他汀治疗老年冠心病心绞痛的疗效观察

Dan Hong injection combined with simvastatin efficacy of treatment of elderly patients with angina pectoris

目的探讨分析丹红注射液联合辛伐他汀治疗老年冠心病心绞痛患者的临床疗效以及不良反应情况。方法选取从2011年7月至2012年10月在本院进行治疗的120例明确诊断的老年冠心病心绞痛的患者作为研究对象,随机平均分为对照组和观察组(各60例)。所有患者均进行一般综合治疗,在此基础上对照组用辛伐他汀进行治疗;观察组在对照组的基础上加用丹红注射液进行治疗。观察两组患者治疗后的临床总有效率、心电图改善以及不良反应等情况。结果治疗后观察组和对照组的总有效率、不良反应发生率分别为95%、3.33%和78.33%、15%,其差异均有统计学意义(P<O.05)。观察组心电图的改善情况明显优于对照组,比较两组差异具有统计学意义(P<O.05)。结论丹红注射液联合辛伐他汀治疗老年冠心病心绞痛患者的临床疗效比单纯应用辛伐他汀治疗老年冠心病心绞痛的临床疗效更显著,心电图缺血情况的改善更明显,不良反应少,安全性高,值得临床推广应用。

Objective To investigate the analysis of Dan Hong injection combined with simvastatin clinical efficacy of the treatment of elderly patients with angina pectoris and adverse reactions. Methods 120 cases confirm the diagnosis of senile coronary heart disease angina patients treated in our hospital from July 2011 to October 2012 for the study, were randomly divided into control group and observation group （60 cases）. All patients underwent general treatment and control group with simvastatin treatment on this basis; Observation group on the basis of the control group plus Danhong injection treatment. Efficiency, ECG improvement and ad- verse reactions in the clinical treatment were observed. Results After treatment, the observation group and control group, the total efficiency of the incidence of adverse reactions were 95%, 3.33% and 78.33%, 15%, and the differences were statistically significant （ P 〈 0. 05 ）. ECG to improve the situation of the observation group than the control group, two groups were compared statistically significant difference （ P 〈 0. 05 ）. Conclu- sion Danhong injection combined with simvastatin in the treatment of the clinical efficacy of elderly patients with angina pectoris is more than the simple application of the clinical efficacy of simvastatin treatment of elderly patients with angina pectoris, ischemic electrocardiographic improvement in the situation is more obvious, ad- verse reactions, safety high, worthy of clinical application.