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神经外科手术中不同组合麻醉用药对应激反应的抑制效果观察 被引量:3

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摘要 目的考察在神经外科手术中不同组合麻醉用药对应激反应的抑制效果。方法将150例行颅脑外科手术患者分为A、B两组各75例,A组麻醉诱导用药为瑞芬太尼+丙泊酚+琥珀胆碱,插管时持续泵注瑞芬太尼,B组麻醉诱导用药及插管时的持续泵注给药为在A组基础上以不同剂量的芬太尼取代瑞芬太尼即可。结果 A、B两组患者在插管前、插管即刻与拔管期的MAP与HR均表现有一定波动,但A组整体较B组明显更轻微;A组患者在拔管即刻与拔管期的整体呛咳发生率为10.7%,B组为42.7%,A组显著低于B组;A组患者的平均睁眼时间与切题答问时间均显著在合理范围内显著早于B组,差异有统计学意义(P<0.05)。结论瑞芬太尼具较好应激反应抑制效果,可作为神经外科手术的麻醉首选用药。
作者 张占军
出处 《中国实用医药》 2013年第23期134-135,共2页 China Practical Medicine
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