通气颗粒对小鼠胃肠功能的影响

Effect of Tongqi Granule(TQG) to gastrointestinal Function

目的:验证通气颗粒的主要功效。方法:采用小鼠胃酚红排空法,正常和脾虚小鼠炭末推进法,醋酸扭体法。结果:通气颗粒中、高剂量组(4,8g·kg^1)灌胃给药可显著促进正常小鼠胃酚红排空运动(P<0.01);通气颗粒中、高2个剂量组(4,8g·kg^1)灌胃给药可显著促进正常小鼠小肠推动功能(P<0.05,P<0.01);通气颗粒低、中、高3个剂量组(2,4,8g·kg^1)连续灌胃给药5d,可显著促进牌虚小鼠小肠推进功能(P<0.05,P<0.01);通气颗粒中、高剂量组(4,8g·kg^1)连续灌胃给药3d对醋酸模型小鼠有显著的镇痛作用(P<0.01)结论:通气颗粒可促进胃肠蠕动。

Objective: To ferify the main effect of Tongqi Granule (TQG). Method: The phenol-red excretion in normal mice stomach, the charcoal powder propulsion function of small intestine in normal and Splen-Weaken mice, and aeetie acid-induced writhing in mice were introdued. Results: TQG could inhibit the phenol-red excretion in normal mice stomach, improving the charcoal powder propulsion function of small intestine in normal and Splen-Weaken mice, inhibiting also acetic acid-induced writhing in mice. Conclusion: TQG can improve the gastrointestinal function in animal.