安徽省2006～2011年麻风病复发患者调查分析

Analysis of recucring-case of lepriasis from 2006 to 2011 in Anhui province

目的了解麻风病复发情况和特点,为防治工作提供依据。方法对2006-2011年安徽省麻风复发病例进行流行病学调查。结果 2006～2011年全省报告麻风复发病例16例,男性14例,女性2例。复发年龄为41～71岁,平均50岁。其中氨苯砜(DDS)单疗治愈复发者9例(PB4例,MB 5例),占56.25%;联合化疗(MDT)治愈复发者7例(PB 4例,MB 3例),占43.75%。治愈至复发的时间为9～402个月,平均200个月。DDS复发时间较晚为124～370个月,MDT为9～184个月。发现方式主要以自报为主,其次是门诊、随访发现。结论麻风病愈后长时间内都有复发的危险,要加强麻风愈后的随访工作。在麻风低流行状态下控制复发和及时发现复发病例是麻风防治工作的重要内容。

Objective To study clinical characteristics and the trends of leprosy relapse cases,and provide evidence for leprosy control.Method Descriptive analysis of data from the national leprosy surveillance system was carried out from 2006 to 2011.Result There were a total of 16 leprosy relapse cases reported during 2006-2011.Of them,there were 14 males and 2 females.Their ages ranged from 41-71 years,and the average age was 50 years.9（4 PB,5 MB） cases were relapsed after DDS monotherapy and 7（4 PB,3 MB） were relapsed after MDT.The proportions of DDS and MDT were 56.25% and 43.75%,respectively.The latent period ranged from 9-402 months with average latent period of 200 months.The latent period of DDS was 124-370 months and MDT was 9-184 months.Most of the patients were found by themselves.Conclusion There is a risk of relapse of leprosy during a long time after being cured,we should strengthen the follow-up work of cured patients.Controlling and finding relapse patients is important work of leprosy control on low prevalence stage.