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盐酸米诺环素滴耳液的制备与临床应用

Preparation and Clinical Application of Minocycline Hydrochloride Ear-Drops
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摘要 目的:研究盐酸米诺环素滴耳液的制备方法。方法:采用UV法测定盐酸米诺环素含量,检测波长为347nm;并对36例化脓性中耳炎患者进行临床观察。结果:测得盐酸卡诺环素的x±s为(100.6±0.73)%。临床有效率为97.2%。结论:本制剂疗效可靠,分析方法快速简便。 Objective: To study the preparation of minocycline hydrochloride ear-drops. Method: The UV-speetropho tometry was used for quantinative analysis. Detection wave-length was an 347nm. The clinieal therapentie effect was observed in 35 patients with otitis media snppurative. Results: The average recovery rates of minocycline hydrochloride was 100.6% RSD o. 73%). The elinieal effective rates was 97.2%. Conclusion: The preparation was effective and the method of determination is smpla.
出处 《中国药师》 CAS 2000年第5期284-285,共2页 China Pharmacist
关键词 盐酸米诺环素 滴耳液 质量控制 化脓性中耳炎 Minocycline hydrochloride Ear-drops Quality control Otitis media suppurativa
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参考文献1

  • 1陈新谦 金有豫.新编药物学(第14版)[M].北京:人民卫生出版社,1996.566.

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