摘要
目的研究梗阻性黄疸(OJ)与肾功能损害因果关系,提出防治对策。方法对409例OJ患者血清胆红素及相关因素与肾功能损害关系进行分析,并对术前、术后血清肌酐水平进行比较。结果黄疸持续时间、血清胆红素水平、胆道感染和低血压状态是OJ引起肾功能损害的主要因素,手术进一步加剧肾功能的损害。结论高胆红素血症、内毒素血症和有效循环血量的改变是肾功能损害的直接致病因素。实施早期综合防治,是保护肾功能、防止肾损害、降低病死率的根本措施。
Objective To investigate the causal relationship between obstructive jaundice（OJ）and renal function impairment and put forward prevention and control measures.Method Relationship between the serum bilirubin and related factors in 409patients with OJ and the renal function impairment was analyzed,and the serum creatinine level before and after surgery was compared.Results Duration of jaundice,the level of serum bilirubin,biliary tract infection and hypotensive state were main factors causing renal function impairment,and the surgery further impaired renal function.Conclusion Hyperbilirubinemia,endotoxemia and change of effective circulating blood volume are direct causes of renal function impairment.Implementing early comprehensive prevention and control is the fundamental measure for protecting renal function,preventing renal impairment and reducing fatality rate.
出处
《保健医学研究与实践》
2013年第3期40-42,共3页
Health Medicine Research and Practice
关键词
梗阻性黄疸
肾功能损害
相关因素分析
防治对策
Obstructive jaundice
Renal function impairment
Related factor analysis
Prevention and control measure
