摘要
目的 :探讨扩张型心肌病的心肌损伤与细胞凋亡的关系。方法 :采用宝灵曼公司的细胞凋亡原位检测试剂盒 (Tunel)对 14例扩张型心肌病心肌组织进行检测。结果 :14例扩张型心肌病心肌组织中 11例检测出有凋亡细胞 ,凋亡细胞阳性指数(AI)范围在 33.14± 12 .5 6～ 2 6 .5 1± 11.2 1之间。结论 :在扩张型心肌病的发生发展中有细胞凋亡机制参与。
Objective:To explore the relationship between myocardial injury of dilated cardiomyopathy and apoptosis Methods:We used Tunel of Boehringer Mannheim Company to examine autoptic myocardial tissues from 14 cases suffering from dilated cardiomyopathy Results:The result showed that the positve rate of apoptosis cell from myocardial tissues of 14 cases is 11/14 The apoptosis index (AI) is 33 14±12 25~26 51±11 21 Conclusion:Apoptosis involved occurrence and development of dilated cardiomyopathy
出处
《广西医科大学学报》
CAS
2000年第5期787-788,共2页
Journal of Guangxi Medical University
基金
广西区卫生厅课题基金!资助 ( 970 1)
关键词
扩张型心肌病
心肌损伤
细胞凋亡
dilated cardiomyopathy
myocardial injury
apoptosis
