台州地区妊娠妇女血清微量元素检测分析

Analysis of blood trace elements in gestation women in Taizhou

目的：了解台州地区孕妇全血微量元素水平变化，为孕期合理补充微量元素提供参考依据。方法：按孕周将808名孕妇分为早孕（〈12周）、中孕（12～28周）、晚孕（〉28周）3个实验组，95名正常体检妇女作为对照组，采用原子吸收分光光度法测定血清中铁、锌、钙、镁、铜的含量。结果：在早、中、晚各孕期，孕妇血清铜含量明显升高（P〈0．05），且随着孕期增加呈升高趋势；孕妇血清钙含量与对照组无显著差异；孕妇各期铁含量，中晚孕期锌含量以及孕晚期镁含量明显低于对照组（P〈0．05）。结论：妊娠妇女应定期进行微量元素的检测，并根据不同孕周，合理补充微量元素，以提高孕产妇及新生儿的健康水平。

Objective： To investigate the changes of serum trace elements levels in pregnant women in Taizhou, to provide instruction for the reasonable supplement of trace elements in gestation. Methods ： According to gestation- al age, eight hundred and eight pregnant women were divided into three experiment groups： early pregnancy group （ 〈 12 weeks） , middle pregnancy group（12 -28 weeks） and late pregnancy group（ 〉28 weeks）. Another 95 non -pregnant women were recruited in control group. Trace elements of Fe, Zn, Ca, Mg and Cu in serum of these women were determined by atomic absorption spectrophotometry. Results： The serum level of Cu in pregnant groups was significantly higher than that in control group（ P 〈 0.05 ） , showing an increasing trend with the increase of ges- tational week ; the serum levels of Ca showed no significant difference between the pregnant women at different gesta- tional period and the non - pregnant women; the levels of Fe in pregnant women, the levels of Zn in middle and late pregnancy group, the levels of Mg in late pregnancy group were significantly lower than those in control groups （ P 〈 0.05 ）. Conclusion： It is necessary for pregnant women to take routine examination of serum trace elements accord- ing to different gestational weeks, trace elements should be supplemented reasonably to improve the health level of pregnant women and neonates.