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Galectin-3在卵巢上皮性肿瘤中的表达及意义

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摘要 目的探讨Galectin-3在卵巢上皮性肿瘤中的表达及其临床意义。方法回顾性分析了2002年至2008年接受治疗的81例上皮性肿瘤标本的临床资料,运用免疫组织化学EnVisionTM二步法检测Galectin-3(半乳糖凝集素-3)在卵巢上皮性肿瘤中的表达情况,对Galectin-3表达进行探究。结果 Galectin-3主要表达于上皮性肿瘤的细胞质之中,极少数位于细胞核上;Galetin-3在卵巢上皮性肿瘤中的表达要显著地高于交界性肿瘤以及囊腺瘤等部位,且它们之间的差异具有统计学意义(P<0.05);Galectin-3在卵巢浆液性肿瘤与黏液性肿瘤中的表达相似,在良性、交界性及恶性肿瘤中两类上皮的表达均无明显差异(P>0.05)。结论 Galectin-3在卵巢上皮性肿瘤中具有一定的表达,能够作为判断卵巢癌预后的参考指标。
作者 刘雪飞
出处 《中国医药指南》 2013年第23期176-177,共2页 Guide of China Medicine
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