腹腔镜胆囊切除术患者手术前后肝外胆管直径变化及与胆囊收缩素CCK关系的临床研究

Clinical Study on the Change of Extrahepatic Bile Duct Diameter of Patients before and after Laparoscopic Cholecystectomy and Its Correction to the Cholecystokinin CCK

目的研究腹腔镜胆囊切除术患者手术前后肝外胆管直径变化及与胆囊收缩素CCK关系。方法选取2011年12月至2012年12月进行腹腔镜胆囊切除术治疗的68例胆囊结石患者为观察组,68例常规体检示健康的人员为对照组,然后将观察组术前、术后3个月、6个月及对照组的肝外胆管直径、血清CCK水平进行比较,并分析二者之间的相关性。结果观察组术前、术后3个月及6个月的肝外胆管直径、血清CCK水平呈现先升后降的趋势,且均高于对照组,P均<0.05,均有显著性差异,经Pearson相关性分析显示肝外胆管直径与血清CCK水平呈正相关。结论腹腔镜胆囊切除术患者手术前后肝外胆管直径变化呈现先升后降,且与CCK呈现正相关。

Objective To study the change of extrahepatic bile duct diameter of patients before and after laparoscopic cholecystectomy and its correction to the cholecystokinin CCK.Methods 68 patients with laparoscopic cholecystectomy from December 2011 to December 2012 were the observation group,68 healthy personal were the control group,then the extrahepatic bile duct diameter and serum CCK of observation group before the operation and at 3rd and 6th month after the operation and control group were compared,and the correction was analyzed.Results The extrahepatic bile duct diameter and serum CCK of observation group before the operation and at 3rd and 6th month after the operation first increased and then decreased,and they were all higher than those of control group,all P0.05,there were all significant differences,extrahepatic bile duct diameter and serum CCK showed positive correlation by Pearson.Conclusion The extrahepatic bile duct diameter of patients before and after laparoscopic cholecystectomy first increases and then decreases,and it showes positive correlation to CCK.