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转录因子T-bet/GATA-3在支气管哮喘中的研究进展 被引量：1

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摘要 T-bet和GATA-3是决定Th细胞向Th1和Th2分化重要转录因子,近来受到越来越多的重视,本文就T-bet和GATA-3在支气管哮喘发病机制及其研究进展做一总结。
作者 屈昌雪 武怡
机构地区 徐州医学院 徐州医学院附属医院儿科
出处 《中国医药指南》 2013年第23期448-449,共2页 Guide of China Medicine
关键词 T-BET GATA-3 支气管哮喘
分类号 R562.25 [医药卫生—呼吸系统]
  • 相关文献

参考文献16

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  • 2Szabo SJ,Sullivan BM Stemmann C,et al.Distinct effects of T-bet in TH1lineage commitment and IFN-gamma production in CD 4 and CD 8 T cells[J].Science,2002,295(5553):338-342.
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二级参考文献23

  • 1顾珺,蒋瑾瑾,沈朝斌,陆磊,戴强,谢匡成,王裕发.玉屏风散对小鼠气道变态反应性疾病Th1/Th2平衡的影响[J].上海中医药杂志,2005,39(7):50-52. 被引量：32
  • 2徐翼,方峰,董永绥,向稚丹,甄宏,李革.巨细胞病毒感染对Th1/Th2细胞分化特异性转录因子T-bet/GATA-3表达的影响[J].临床儿科杂志,2005,23(7):437-440. 被引量：8
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  • 6Ngoc PL,Gold DR,Tzianabos AO,et al.Cytokines,allergy,and asthma.Curr Opin Allergy Clin Immunol,2005,5:161-166.
  • 7Szabo SJ,Sullivan BM,Stemmann C,et al.Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells.Science,2002,295:338-342.
  • 8Mullen AC,High FA,Hutchins AS,et al.Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.Science,2001,292:1907-1910.
  • 9Szabo SJ,Kim ST,Costa GL,et al.A novel transcription factor,T-bet,directs Th1 lineage commitment.Cell,2000,100:655-669.
  • 10Dow SW,Schwarze J,Heath TD,et al.Systemic and local interferon gamma gene delivery to the lungs for treatment of allergen-induced airway hyperresponsiveness in mice.Hum Gene Ther,1999,10:1905-1914.

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中国医药指南
2013年 第23期

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