期刊文献+

蜂胶的抗氧化活性及其分子机制研究进展 被引量:17

Advance in studies on antioxidant activity of propolis and its molecular mechanism
原文传递
导出
摘要 蜂胶是蜜蜂工蜂采集的植物树脂与其上颚腺、蜡腺等的分泌物混合而成的胶黏性物质,具有广泛的药理活性及保健功能。蜂胶的抗氧化活性一直被认为是蜂胶最重要的生物活性之一。该文针对不同地理来源、不同提取方法获得的蜂胶提取物以及蜂胶中几种重要单体活性成分的抗氧化活性方面的研究进展进行了综述,并总结了蜂胶及其单体成分发挥抗氧化活性的可能存在的分子机制,旨在为更深入地研究蜂胶的药理活性提供思路,同时也为蜂胶产品的深度开发提供参考。 Propolis is an adhesive substance mixed with plant resins collected by honeybees (Apis mellifera) and secretions from their mandibular gland and wax gland, with wide pharmacological activity and healthcare functions. Its antioxidant activity has long been regarded as one of the most important biological activities of propolis. This article summarizes studies on the antioxidant ac- tivity of propolis extracts from different geographic origins and with different extraction methods, as well as several important monomer active ingredients in propolis, and concludes the potential molecular mechanism of antioxidant activity of propolis and its monomer in- gredients, with the aim of providing ideas for further studies on pharmacological activity of propolis, as well as reference for in-depth development of propolis products.
出处 《中国中药杂志》 CAS CSCD 北大核心 2013年第16期2645-2652,共8页 China Journal of Chinese Materia Medica
基金 国家自然科学基金项目(31272512) 国家蜂产业技术体系专项(CARS-45)
关键词 蜂胶 单体成分 抗氧化活性 分子机制 propolis monomer ingredient antioxidant activity molecular mechanism
  • 相关文献

参考文献4

二级参考文献54

  • 1胡福良,李英华,朱威,陈民利,应华忠.蜂胶预防大鼠急性肺损伤的作用及其机制[J].中国药学杂志,2004,39(6):432-434. 被引量:9
  • 2徐叔云.抗炎免疫药理学研究十年进展[J].中国药理学通报,1996,12(1):1-6. 被引量:28
  • 3Vassya S, Bankova V. Propolis: recent advances in chemistry and plant origin[J]. Apidologie, 2000, 31:3-15.
  • 4Marcucci M C, Ferreres F, Garcia-Viguera, et al. Phenolic compounds from Brazilian propolis with pharmacological activities [J]. Journal of Ethnopharmacology, 2001, 74: 105-112.
  • 5Wang L, Mineshita S, Ga I. Antiinflamatory effects of propolis [J]. Japanese Journal of Pharmacological Therapeutics, 1993, 24:223-226.
  • 6Marcucci M C. Propolis: chemical composition, biological properties and therapeutic activity[J]. Apiddogie, 1995, 26:83-99.
  • 7Arjun H, Banskota, Takema N, et al. Antiproliferative activity of the Netherlands propolis and its active principles in cancer cell lines [J]. Jounal of Enthnopharmacology, 2002, 80: 67-73.
  • 8LU Guang(卢光).Receptor signal transduction system and disease(受体信号转导系统与疾病)[M].Jinan:Shandong Science and Technology Press.1999,368—397.(in Chinese).
  • 9WEI Er-qing(魏尔清).Recent advances in pharmacology—signal,protein gene,gene and modern pharmacology(药理学前沿-信号、蛋白因子、基因与现代药学)[M].Beijing:Science Press.1999:224—240.(in Chinese).
  • 10GENG Dong—sheng(耿东升).The anti—inflammatory and immumoregulatory effect of berberine [J].Pharmacology Journal of the PLA(解放军药学学报),2002,16(6):317-320.(in Chinese).

共引文献29

同被引文献135

引证文献17

二级引证文献77

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部