不完全川崎病合并冠状动脉损害高危因素分析

Analysis of Risk Factors of Incomplete Kawasaki Disease and Coronary Artery Lesion

目的:分析不完全川崎病合并冠状动脉损害发病的高危因素。方法:回顾性分析112例不完全川崎病患儿的病例资料,将12个可能与冠状动脉损害相关的因素进行回归分析。结果:血浆白蛋白<30g/L、发病年龄与冠状动脉损害存在相关性(P<0.05);血小板计数≥450×109/L、发热天数≥10天与冠状动脉损害可能有关,但无统计学意义(P>0.05)。血浆白蛋白<30g/L、发病年龄均入选Logistic方程,Logistic方程为Y=-0.116X1+0.463X2-1.641,其中血浆白蛋白<30g/L对不完全川崎病合并冠状动脉损害的贡献相对较大。结论:不完全川崎病合并冠状动脉损害的高危因素为低血浆白蛋白水平和低发病年龄。

Objective：To analyze the risk factors of incomplete Kawasaki disease and coronary artery lesion.Methods：The clinical data of 112 children with incomplete Kawasaki disease were retrospectively analyzed,12 risk factors with of coronary artery lesions were analyzed as well.Results：There was a correlation between the plasma albumin 30g＇L,age of onset and the severity of coronary artery lesion（P0.05）,may be related to platelet count ≥ 450×109＇L,fever days ≥10 days and coronary artery lesion,but without statistical significance（P0.05）.Plasma albumin 30g＇L,age of onset were included in the study of Logistic equation,Logistic equation was y=-0.116X1＋0.463X2-1.641,plasma albumin30g/L contribution to the incomplete Kawasaki disease.Conclusion：The risk factors of incomplete Kawasaki disease and coronary artery lesion were decreased plasma albumin level and the age of the children.