血浆同型半胱氨酸水平与老年血管性痴呆相关性研究

Research on the Correlation between Plasma Homocysteine Levels and VascuLar Dementia

目的:研究血浆同型半胱氨酸(Hcy)水平变化与老年血管性痴呆的相关性。方法:检测268例老年血管性痴呆患者和268例同龄健康老年人血浆Hcy的含量,比较两组Hcy血浆水平的差异;分析血浆Hcy水平与痴呆程度的关系。结果:老年血管性痴呆患者血浆Hcy水平较正常健康老年人明显增高,且其Hcy血浆水平随血管性痴呆的严重程度而增加。结论:血浆Hcy含量增高可能是导致老年血管性痴呆的危险因素之一。

Objective：To study the plasma homocysteine（Hcy） levels and vascular dementia correlation.Methods：268 cases of vascular dementia patients and 268 cases of healthy older peers plasma Hcy levels were compared between the different levels of Hcy in plasma;analysis of plasma Hcy levels and the relationship between the degree of dementia.Results：Patients with vascular dementia plasma Hcy levels were significantly higher than normal healthy elderly,and its plasma Hcy levels increased with vascular dementia severity increases.Conclusion：increased Plasma Hcy levels may lead to vascular dementia risk factors.