黄芪和复方丹参注射液对充血性心力衰竭患者临床疗效的影响

Clinical Effect of Radix Astragali seu Hedysari Injection Combined with Compound Radix Salviae Miltiorrhizae Injection on Congestive Heart Failure

将 6 4例充血性心力衰竭患者随机分为常规治疗组 (简称常规组 ,30例 )和常规治疗联合静滴黄芪和复方丹参注射液组 (简称中药组 ,34例 ) ,观察两组的临床疗效和超声心功能及血浆脂质过氧化物 (LPO)、超氧化物歧化酶 (SOD)的变化。结果中药组总有效率 (94 .12 % )高于常规组 (76 .6 7% ) ,两组比较P <0 .0 5;两组治疗后超声心功能均有改善 (与治疗前比较P <0 .0 5或P <0 .0 1)。且中药组比常规组效果显著(P <0 .0 5) ;两组治疗后LPO下降 ,SOD上升 (P <0 .0 5或P <0 .0 1) ,而且中药组LPO下降、SOD上升比常规组更为显著 (P <0 .0 5)。

Sixty_four cases of congestive heart failure (CHF) were randomly allocated to two groups: routine treatment group (n=30) and Chinese medicine group (n=34) which received intravenous drip of Radix Astragali seu Hedysari Injection combined with Compound Radix Salviae Miltiorrhizae Injection on the basis of routine treatment. Clinical effect, heart function (evaluated by echocardiography), and the plasma content of lipid peroxide (LPO) and superoxide dismutase (SOD) were observed. The results showed that the total effective rate is 94.12% in Chinese medicine group and 76.67% in the routine treatment group (P< 0.05 ). Heart function was improved, LPO content decreased and SOD level increased in both two groups after treatment, the difference being significant as compared with before treatment (P< 0.05 or? P< 0.01 ), and the above effects were more obvious in Chinese medicine group than in the routine treatment group (P< 0.05 ). It is indicated that Chinese medicine combined with western medicine is superior to western medicine only for the treatment of CHF.