脑血管疾病时白细胞、血清肌酸激酶的变化

Changes in blood WBC and CK levels in patients with cerebrovascular disease

目的：本文通过对临床常见脑血管疾病（脑出血、脑血栓形成、脑栓塞）患者血白细胞（ＷＢＣ）和血清肌酸激酶（ＣＫ）的测定，来探讨ＷＢＣ、ＣＫ的变化及其临床意义。方法：９０例脑血管病患者及２５例健康人的ＷＢＣ及ＣＫ均采用全自动血细胞分析仪和全自动血液生化仪测定。结果提示：脑血管疾病患者ＷＢＣ、ＣＫ较健康人高（Ｐ＜０．０５）；且脑出血患者出血破入侧脑室者较未破入侧脑室者显著增高（Ｐ＜０．０１）；同时死亡患者ＷＢＣ、ＣＫ显著高于未死亡脑血管疾病患者（Ｐ＜０．０１）。结论：ＷＢＣ和ＣＫ可以作为判断脑血管疾病病情程度的客观指标，其急剧升高预后不良。

Objective: To measure white blood cell(WBC) and creatine phosphokinase (CK) in patients with Cerebrovascular disease (Cerebral heamorrhage cerebral embolism Cerebral thrombosis) and healthy persons and study the changes in blood WBC and CK levels in patients with cerebrovascular disease and healthy persons. Method: We collected blood from 90 patients with cerebrovascular disease and 25 healthy persons and measured it by the automatic blood cell analysis instrument and the automatic blood and biochemistry analysis instrument. Results: WBC and CK levels in patients with cerebrovascular disease bleeding into the lateral ventricle were significantly elevated compared with patients with cerebrovascular disease whose blood didn't run into the lateraventricle (p<0.01); WBC and CK levels in death patients were significantly elevated than those of the survivals. Conclusions: We may take the WBC and CK as an objective criteria for the determination of the degree of cerebrovascular disease (p<0.01) and rapidly increased WBC and CK levels leads to a doubtful prognosis.