前白蛋白联合C反应蛋白检测在新生儿早期感染诊断的应用价值

Application Value Analysis of Prealbumin Ioint C Reactive Protein Test in the Diagnosis of Early Neonatal Infection

目的:分析血清前白蛋白(PA)联合C反应蛋白(CRP)检测在新生儿早期感染诊断中的应用价值,为新生儿感染诊治提供参考。方法:对在本院分娩的82例新生儿进行感染监测,感染组31例,未感染组51例,对两组新生儿分别采用免疫比浊法定量检测法测定血清PA及CRP水平,计算PA、CRP检测诊断新生儿早期感染的敏感性、特异性。结果:感染组PA为(99.6±12.8)mg/L,低于未感染组的(258.4±24.7)mg/L(P<0.01);感染组CRP为(70.8±11.2)mg/L,高于未感染组的(4.2±1.1)mg/L(P<0.01);PA诊断敏感性、特异性分别为96.77%、82.35%,CRP诊断敏感性、特异性分别为87.10%、96.08%。结论:血清PA联合CRP检测可提高新生儿早期感染诊断的敏感性及特异性,可作为新生儿感染诊断的可靠依据。

Objective： To analyze the application value of PA joint CRP test in the diagnosis of early neonatal infection,and provide a reference for the diagnosis and treatment of neonatal infection.Methods：82 cases of neonatal were infection surveillance,31 cases in infected group,51 cases in uninfected group,two groups were used turbidimetric immunoassay quantitative detection method for the determination of serum PA,CRP levels,calculate the sensitivity and specificity of PA,CRP test in the diagnosis of early neonatal infection.Results：PA level of infected group was（99.6±12.8） mg/L,lower than uninfected group of（258.4±24.7） mg/L（P0.01）;CRP levels of infection group was（70.8±11.2）mg/L,higher than uninfected group of（4.2±1.1）mg/L（P0.01）;diagnostic sensitivity,specificity of PA test was 96.77%,82.35%,diagnostic sensitivit,specificity CRP test was 87.10%,96.08%.Conclusion：Serum PA jiont CRP test can improve the sensitivity and specificity of the diagnosis of early neonatal infection,can be used as a reliable basis for the diagnosis of neonatal infection.