精神分裂症近期结局的影响因素及干预对策

The Influential Factors of the Short-term Outcome of First Episode Schizophrenic Patients and Intervention Measure

目的 :分析首次发病精神分裂症患者近期结局的影响因素 ,为制定有效的干预对策提供理论依据。方法 :以一系列标准化评定工具 ,对符合CCMD - 2 -R诊断标准的 16 0例首发精神分裂症患者进行为期 2a的随访评估 ,对所得资料进行单因素分析和多元逐步回归分析。结果 :首发精神分裂症 2a随访时结局良好者达 5 9 9% ,影响其近期结局的主要因素为 :随访期服药治疗情况、社会支持、思维贫乏、注意障碍、病前职业功能水平、意志缺乏。结论 :首发精神分裂症患者近期结局较好 ,受生物、心理、社会等多方面因素的影响 ,在一定程度上可以人为干预 。

Objective:To analyse the influential factors of the short-term outcome of first episode schizophrenic patients and give theoretical accordance for making intervention measure.Methods:160 cases first episode schizophrenic patients were investigated and assessed using standard assessment instruments,the information was analyzed by means of multivariate analyses of step wise regression.Results:59.9% of first episode schizophrenic patients had a good global outcome at the end of two years follow-up,the main influential factors are maintenance treatment during follow-up,social supports,poverty of thought,attention disturbance,premorbid level of occupational function and abulia.Conclusion:The findings suggest that the first episode schizophrenic outcome was good,the factors can be dealt with play an important role in certain degree.At last making corresponding intervention measure.