滇西乌头化学成分研究

Chemical Constituents of Aconitum bulleyanum

目的:研究滇西乌头Aconitum bulleyanumDiels.的化学成分。方法:采用现代色谱技术对滇西乌头三氯甲烷层浸膏进行分离和纯化,根据化合物光谱数据进行结构鉴定。结果:分离鉴定了7个化合物,分别为:滇乌碱(1)、crassicaudine(2)、黑乌弱碱(3)、查斯马克宁定(4)、草乌甲素(5)、大渡乌碱(6)、β-谷甾醇(7)。结论:其中,化合物2～7为首次从该植物中分离得到。

Objective： To study the chemical constituents of chloroform fraction from Aconitum bulleyanum. Methods： The compounds were isolated by various chromatographic techniques and identified by spectroscopic methods. Resuhs：7 compounds were obtained and identified as yunaconitine （ 1 ）, crassicaudine （ 2 ）, foresaconitine （ 3 ）, chasmaconitine （ 4 ）, bulleyaconitine A （ 5 ）, franchetine （6）, and β-sitosterol （7）, Conclusion ： Compounds 2 - 7 are isolated from this plant for the first time.