他汀适应证升级引发的思考——冠心病管理从控制危险因素到管理动脉粥样硬化

Thinkings Induced by Statins Indications Upgrade——Coronary Artery Disease Treatment from the Risk Factors Control to the Management of Atherosclerosis

从循证医学的角度探讨冠心病患者的管理,循证医学证明控制危险因素大幅度降低冠心病死亡,危险因素控制达标成为冠心病现代治疗的主要方向。动脉粥样硬化是进展性疾病,斑块的进展破裂是导致事件的罪魁祸首,仅仅控制危险因素不足以从根本上治愈冠心病。透过现象,从控制危险因素达标到管理动脉粥样硬化,转变现有的治疗观念,引入新的动脉粥样硬化管理理念,即"Treating Arteries Instead of Risk Factors"。

We discuss the management of coronary artery disease（CAD） patients from the medicine from the evidence-- based medicine perspective. Evidence--based medicine has proved that the control of risk factors significantly reduced the mortality of CAD. Risk factor control standard become the main direction of the modern treatment of CAD. Atherosclerosis is a progressive disease, plaque rupture is the culprit of cardiovascular events. Only control of risk factors is not sufficient to radically cure CAD. Through the phenomenon, transformed the current therapy options from reaching the risk factors control standard into managing the atherosclerosis, and introduced a new management concept of atherosclerosis： Treating Arteries Instead of Risk Factors.