摘要
目的:建立天麻胶囊中非法添加吲哚美辛的检测方法。方法:采用TLC快速筛选、HPLC-PDA法进行定量检验以及UPLC-MS法进行结构确认。结果:建立的方法能鉴别并确认添加的吲哚美辛,灵敏度高,专属性好。结论:该方法简便、快速,结果准确,可用于检测天麻胶囊中非法加入的吲哚美辛成分。
Objective:To establish a method to identify illegally added indometacin in Tianma capsules.Method:Indometacin in Tianma capsules was fast screened by TLC,quantitatively inspected by HPLC-PDA and structurally confirmed by UPLC-MS.Result: Indomethacin could be identified.The method was with high sensitivity and good specificity.Conclusion:The method is simple,reliable and accurate,and can be used in the detection of illegally added indometacin in Tianma capsules.
出处
《中国药师》
CAS
2013年第8期1139-1141,共3页
China Pharmacist