组织工程研究文献计量学分析

BIBLIOMETRIC ANALYSIS ON TISSUE ENGINEERING RESEARCH LITERATURES

目的 掌握组织工程研究现状和发展水平、推断研究热点及预测学科发展趋向。方法 检索MEDL INE生物医学文献数据库 1987年～ 1999年组织工程研究的全部文献 314篇 ,利用文献计量学方法对文献年代、国别、文种、主要期刊、多产作者及主题词词频分布进行分析。结果 自 1990年起 ,组织工程研究文献量逐年近乎呈倍数增加 ,且 1998年～ 1999年发表文献占总文献量的 5 7.96 %。全部文献来自 15个国家 ,6种出版文字 ,140种期刊。美国发表文献占 6 4.97%。英文文献占 93.95 %。产文 5篇以上的作者 2 0位。种子细胞、移植学、支架材料与细胞外基质、体内植入、潜在应用、人工替代物、聚合物、组织培养及生物遗传学的词频累计达 94.93%。结论组织工程研究的主要产文国为美国、英国、荷兰和德国 ;英文为主要文种 ;《J- Biomed- Mater- Res》等 15种期刊为其核心期刊 ;种子细胞、移植学、支架材料与细胞外基质及体内植入为组织工程研究的热点和重点。

Objective To comprehend the progress of tissue engineering research and speculate its developmental trends. Methods MEDLINE search was conducted to retrieve the papers published between 1987 to 1999 under the main headings of tissue engineering. Years, nationalities, languages, journals, authors and heading frequencies of 314 papers were analyzed by bibliometrics. Results Since 1990, the number of tissue engineering research literatures had doubled, and papers between 1998 and 1999 made up 57.96% of the total papers. All papers came from 15 nations, in 6 languages and 140 journals; 64.97% came from United States and 25.79% from England, Netherlands and Germany; 93.95% was in English; 42.04% was published on 15 journals. Vacanti JP and 19 other authors presented 5 to 24 papers. Heading frequencies were cytology 22.89%, transplantation 13.30%, scaffolds and extracellular matrixes 11.72%, implanting 10.60%, polymers 8.91%, potential applications 8.91%, artificial substitutes 6.88%, tissue culture 6.70% and biogenetics 4.96%. Conclusion Tissue engineering literatures mainly come from United States, England, Netherlands and Germany. English is the major language. J Biomed Mater Res and 14 other journals are important journals about tissue engineering research. Vacanti JP and 19 other authors are prolific authors. Cytology, transplantation, scaffolds and extracellular matrixes and implanting are hot topics and key points on tissue engineering research.