导尿管相关性尿路感染的病因分析及治疗策略

Causes of catheter-related urinary tract infections and treatment strategies

目的总结由于留置导尿管而引起的尿路感染(UTI)病因分析以及治疗策略。方法将80例UTI患者随机分为治疗组和对照组各40例,对照组采用静脉注射头孢曲松治疗,治疗组采用静脉注射头孢曲松联合口服氧氟沙星治疗。结果 UTI患者检出病原菌主要为革兰阴性杆菌,其中以大肠埃希菌、克雷伯菌属较为常见,分别占33.80%、14.08%;治疗组总有效率为100.00%,对照组总有效率为75.00%,两组疗效比较,差异有统计学意义(P<0.05)。结论 UTI的菌群主要为革兰阴性杆菌,静脉注射头孢曲松联合口服氧氟沙星胶囊的方法对于革兰阴性杆菌有抑制作用,所以对治疗UTI有一定疗效。

OBJECTIVE To summarize the causes of urinary tract infections（UTI）induced by the catheter indwelling and put forward the treatment strategies.METHODS A total of 80cases of patients with UTI were randomly divided into the treatment group and the control group with 40cases in each,then the control was treated with intravenous ceftriaxone,while the treatment group was treated with intravenous ceftriaxone combined with oral ofloxacin.RESULTS The gram-negative bacilli were the main pathogens isolated from the UTI patients,among which the Escherichia coli and the Klebsiella were the most common species,accounting for 33.80% and 14.08%,respectively.The overall effective rate of the treatment group was 100.00%,the control group 75.00%,as compared with the clinical efficacy between the two groups,the difference was significant（P 0.05）.CONCLUSIONThe gram-negative bacilli are the predominant pathogens causing UTI,and the intravenous ceftriaxone combined with oral administration of ofloxacin capsules can inhibit the gram-negative bacilli,therefore,it can achieve certain curative effect on treatment of UTI.