期刊文献+

Cyclodextrin-Based Porous Nanocapsules

Cyclodextrin-Based Porous Nanocapsules
原文传递
导出
摘要 Cyclodextrins (CDs) are regarded as one kind of the most important and promising macrocyclic oligosaccha- rides, which contain hydrophobic internal cavities capable of hosting various guest molecules. CDs are water-solu- ble, non-toxic, commercially available as well as low-cost. Because of these favorable characteristics, cyclodextrin chemistry has created a great number of interesting works covering different fields, in particular CD-based porous nanocapsules (CDPNCs). Chemical cross-linking is an important way developed to prepare CDPNCs. CDPNCs can be obtained using different cross-linkers and preparation methods, such as homogeneous method, miniemulsion po- lymerization, and emulsion-solvent evaporation method. Because of cross-linking, a three-dimensional network is built which forms the porous structure in CDPNCs with the cavities of CDs. Attributed to the porous structure, CDPNCs exhibit excellent performances in encapsulation of targeted molecules and realization of controllable re- lease, indicating a promising prospect in applications such as drug delivery systems and environment protection. Cyclodextrins (CDs) are regarded as one kind of the most important and promising macrocyclic oligosaccha- rides, which contain hydrophobic internal cavities capable of hosting various guest molecules. CDs are water-solu- ble, non-toxic, commercially available as well as low-cost. Because of these favorable characteristics, cyclodextrin chemistry has created a great number of interesting works covering different fields, in particular CD-based porous nanocapsules (CDPNCs). Chemical cross-linking is an important way developed to prepare CDPNCs. CDPNCs can be obtained using different cross-linkers and preparation methods, such as homogeneous method, miniemulsion po- lymerization, and emulsion-solvent evaporation method. Because of cross-linking, a three-dimensional network is built which forms the porous structure in CDPNCs with the cavities of CDs. Attributed to the porous structure, CDPNCs exhibit excellent performances in encapsulation of targeted molecules and realization of controllable re- lease, indicating a promising prospect in applications such as drug delivery systems and environment protection.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2013年第5期569-576,共8页 中国化学(英文版)
基金 The financial support of the National Science Foundation of China,the Ministry of Science and Technology of China (National Major Scientific Research Program,Grant No.2011CB932500) is acknowledged
关键词 cyclodextrins NANOCAPSULES POROUS cross-linking cyclodextrins, nanocapsules, porous, cross-linking
  • 相关文献

参考文献86

  • 1Del Valle, E. M. M. Process Biochem. 2004, 39, 1033.
  • 2Zhang, J. X.; Ma, P. X. Nano Today 2012, 5, 337.
  • 3Liu, Y.; Han, B.-H.; Chen, Y.-T. J. Phys. Chem. B 2002, 106, 4678.
  • 4Zhang, M.; Gao, Y.; Hu, R.-Z.; Shi, Z. Chin. Chem. Lett. 2008, 19, 1139.
  • 5Song, L.-X.; Wang, H.-M.; Teng, C.-F.; Bai, L.; Xu, P.; Guo, X.-Q. Chin. J. Chem. 2008, 26, 1702.
  • 6Huang, H.; Liu, F.; ]ia, B.-X.; Xu, K.-H.; Chen, Z.-Z.; Tang, B. Chin. J. Chem. 2007, 25, 337.
  • 7Yang, Y.-S.; Zhang, Y.-P.; Yang, A.-M.; Lu, R.-H.; Shi, Y.-P.; Shi, G.-F. Chin. J. Chem. 2005, 23, 775.
  • 8Rajewski, R. A.; Stella, V. J. J Pharmaceut. Sci. 1996, 85, 1142.
  • 9Loftsson, T.; Masson, M.; Brewster, M. E. J. Pharmaceut. Sci. 2004, 93, 1091.
  • 10Mashhood, A. S.; Fahmeena, A. Chin. J. Chem. 2006, 24, 665.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部