急性一氧化碳中毒几种相关生化指标的诊治意义

Diagnostic and Therapeutic Significance of Several Biochemical Indicators of Acute Carbon Monoxide Poisoning

急性一氧化碳中毒(acute carbon monoxide poisoning,ACOP)是临床常见的急重症之一。血碳氧血红蛋白(carboxyhemoglobin,COHb)水平是临床诊断ACOP常用的检测指标,但其并不能很好地反映病情状况。本文对S100β蛋白、神经元特异性烯醇酶(neurone specific enolase,NSE)、心肌肌钙蛋白I(cardiac troponinⅠ,cTnI)等几种ACOP生化指标研究进行简要概述,以供临床医生参考。

Acute carbon monoxide poisoning （ACOP） is a common clinical critical emergency. Carboxyhemoglobin （COHb） is a general indicator of ACOP clinical diagnosis, but cannot reflect the pathogenetic condition accurately. The present article reviewed several biochemical indicators of ACOP, including S100β protein, neuron specific enolase （NSE）, and cardiac troponin I （cTnI） for occupational clinical reference.