乐免敏在变态反应性结膜炎中的临床应用

Alomide in treatment of allergic conjunctivitis

目的 评价乐免敏在变态反应性结膜炎中的疗效和安全性。方法 选择变态反应性结膜炎患者３０例（６０眼，男 １７例，女 １３例，平均年龄 ２５ａ±ｓ６ａ），随机分为二组给予局部单独滴用乐免敏或色苷酸钠．每日 ４次，每次１～２滴。结果 乐免敏组７天、１４天总有效率分别为３５．０％、８５．０％，相应色苷酸钠组分别为２２．２％、３０．０％，经统计学检验 １４天疗效差异有显著性（Ｐ＜０．０５）；不良反应为 ４０． ０％患者有轻度烧灼感．可以耐受、未见其它不良反应。结论 乐免敏作为一种新型的肥大细胞膜稳定剂治疗变态反应性结膜炎效果良好，疗效优于色苷酸钠，且不良反应少。

Objective To evaluate the therapeutic effect and safety of alomide in the treatment of allergic conjunctivitis. Method 30 Patients (60 eyes, M 17, F 13;age 25a ±s6a) with allergic conjunctivitis were respectively given alomide and sodiumi cromoglycate eye drops,1-2 drops,qid,for 2 weeks as a course. Result The total effective rate was 85. 0% in alomide group and 30. 0% in sodiumi cromoglycat group after using 2 weeks (P< 0. 05). The rate of adverse reaction was 40. 0%,mainly associated with slight sensation of stitch. Conclusion Alomide eye drops is effective for allergic conjunctivtis.