慢性肾炎中医证型与尿表皮生长因子的关系探讨

Exploration on Relationship Between Urine EGF & TCM Syndromes in Chronic Glomerulonephritis

为了探讨慢性肾炎中医证型与尿表皮生长因子 ( EGF)的关系 ,采用放射免疫法测定尿EGF含量 ,结果显示慢性肾炎各中医证型中尿 EGF含量差异显著 ( P<0 .0 1) ,肺肾气虚组 >气阴两虚组 >肝肾阴虚组 >脾肾阳虚组 >正常人组。说明尿

Objective:To explore the relationship between urine EGF and TCM syndromes in patients with chronic glomerulonephritis(CGN).Methods:The level of urine EGF was measured using radioimmunoassay(RIA).Results:The EGF levels was significantly different among TCM syndromes in CGN patients(P<0.01).The EGF level of the deficiency syndrome of lung and kidney Qi was the highest,then the deficiency syndrome of both Qi and Yin,deficiency syndrome of liver and kidney Yin,the healthy controls followed in sequence.Conclusion:Urine EGF can serve as a reference index of TCM syndrome differentiation of CGN patients.