氩离子凝固术治疗十二指肠息肉的临床研究

Clinical Study of Endoscopic Argon Plasma Coagulation in Treatment of Duodenal Polyps

目的探讨应用氩离子凝固术(APC)治疗十二指肠息肉的疗效及安全性,并与微波治疗十二指肠息肉的效果进行比较研究。方法选择2008年12月至2013年2月经胃镜检查确诊的151例十二指肠息肉患者按治疗方式随机分为两组:APC组75例,微波治疗组76例。观察比较两组患者的息肉根除率、并发症、治疗疗程及费用。结果(1)APC组和微波治疗组的息肉根除率分别为90.6%、66.9%,差异有非常显著性(P<0.01);(2)APC组治疗期间有8例出现轻度的并发症,给予对症处理后消失,微波治疗组有18例出现糜烂,7例出现上消化道出血,对症治疗后痊愈;(3)两组患者住院时间比较无统计学差异(P>0.05),微波治疗组住院费用高于APC组(P<0.05)。结论氩离子凝固术治疗十二指肠息肉效果明显,副作用小,安全可靠,值得临床推广应用。

Objective To explore the effects and safety of endoscopic argon plasma coagulation and microwave therapy on duodenal polyps. Methods From December 2008 to February 2013,a total of 151 patients with duodenal polyps were ran- domly divided into two groups, one group treated with APC （ n = 75 ） , another with microwave therapy, then contrasted the thera- py effect, related complications, length and costs of hospitalization of the two methods. Results The pathologic change＇ s disap- pearance rate through endoscope in the APC group＇s was 90.6% ,the microwave group＇s was 66.9% （P 〈0.01 ）. Complication：7 patients in the microwave group had hemorrhage of upper digestive tract, the APC group has no one. The length of hospi- talization was similar in 2 groups （ P 〉 0. 05 ） , and the cost of hospitalization in the microwave group was significantly higher than that of the APC group （ P 〈 0.05 ）. Conclusion APC showed higher efficacy and safety in the treatment on duodenal polyps, which is worthy of being spread in clinical application.