急性心肌梗塞后QT离散度与缺血性猝死的关系

The relationship between QT dipersion and ischemic sudden death after acute myocardial infarction

目的 :急性心肌梗塞 (AMI)患者血管再通与否与 QT离散度 (QTd)关系对心肌缺血性猝死的预测价值。方法 :AMI患者在发病 6 h内用尿激酶静脉溶栓 ,通过间接指标判断血管再通与否。溶栓后 3h和 2 4h测量的 QT和 QTc间期、QTd 和 QTcd为 1 2导联心电图最大与最小 QT和 QTc间期之差。结果 :血管再通与否和心肌缺血性猝死 QTd 有显著性差异 (P<0 .0 1 )。结论 :QTd 是预测 2 4h内

Objective:Comparision of QT dispersion in AMI patients with recanalization or without recanalization provides predicted value of ischemic sudden death.Method:Patients with AMI were in travenously injected with urokinase during the initial 6 hours coronary artery recanalization or no recanalization were judged by indirective characteristics.QT and QT c were measured at the first 3 hours and 24 hours after thrombolytic therapy.Concomitantly,QT d and QT cd were differences calculated separately between the longest and the smallest in QT and QT c.Result:QT d in patients with ischemic heart sudden death was significantly different between coronary artery recanalization and no recanalization(P<0.01).Conclusion:QT d is the independent risk factor that can predicte malignant arrhythmias and sudden death during acute myocardial infarction 24 hours.