期刊文献+

降压治疗后续效应对老年高血压患者认知功能的影响

下载PDF
导出
摘要 目的探讨降压治疗后续效应对老年高血压患者认知功能的影响。方法参加过老年高血压患者治疗试验主试验的受试者194例,主试验结束后再对其进行2年开放治疗。按原分组标准分为两组:原药物治疗组(n=105)和对照组(n=89)。开放治疗始末采用简易精神状态检查量表(MMSE)检查两组患者的认知功能。结果治疗组MMSE总分、定向力、即刻记忆力、注意力和计算力下降幅度明显低于对照组(P均<0.01);两组记忆力、语言能力变化幅度差异无统计学意义(P分别=0.09,0.06)结论对老年高血压患者进行降压治疗,其后续效应可以延缓老年高血压患者认知功能的下降速度。
作者 宋忠海
出处 《中国医药指南》 2013年第18期119-120,共2页 Guide of China Medicine
  • 相关文献

参考文献6

  • 1张钰聪,汤哲.北京市社区老年人群血压水平与认知功能变化的4年纵向研究[J].中华流行病学杂志,2004,25(10):833-836. 被引量:18
  • 2Cicconett i P,Cost arelia M,Moise A,et al.Blood pressur e variability and cognit ive funct ion in older hypert ens ives[J].Arch Gerontol Geriatr Suppl,2004(9):63-68.
  • 3刘振东,路方红,董元丽,赵颖馨,王舒健,孙尚文.老年高血压患者血压昼夜节律及颈动脉粥样硬化与认知功能损害[J].中华高血压杂志,2009,17(9):821-824. 被引量:15
  • 4Guo Z,Fratiglioni L,Winblad D,et al.Blood pressure and perform-ance on the mini-Mental state examination in the very old.Cross-sectional and longitudinal data from the kungsholmen project[J].Am J Epidemiol,1997,145(12):1106-1113.
  • 5Txourio C,Dufouil C.Cognitive decline in individuals with high blood pressure:a longitudinal study in the elderly[J].Neurology,1999,53(9):1948-1952.
  • 6Peila R,White LR,Masaki K,et al.Reducing the risk of dementia:efficacy of long-term treatment of hypertension[J].Stroke,2006,37(5):1165-1170.

二级参考文献17

  • 1张钰聪,汤哲.老年人高血压与认知功能[J].高血压杂志,2005,13(7):399-402. 被引量:15
  • 2Kanemaru A, Kanemaru K, Kuwaiina I. The effects of shortterm blood pressure variability and nighttime blood pressure levels on cognitive function[J]. Hypertens Res, 2001,24~19 24.
  • 3Cicconetti P, Costarelia M, Moise A, et al. Blood pressure variability and cognitive function in older hypertensives[J]. Arch Gerontol Geriatr Suppl,2004,9 : 63-68.
  • 4Seux ML, Thijs L, Foritte F, et al. Correlates of cognitive status of old patients with isolated systolic hypertension: the Syst Eur Vascular Dementia Project[J]. J Hypertens, 1998,16 : 963-969.
  • 5Hamada T, Chikamori T, Nishinaqa M, et al. Long-term effect of hypertension on neurobehavioral and cardiac function in the apparently healthy communitydwelling elderly: a 5-year follow-up study[J]. Nippon Ronen Iqakkai Zasshi, 2003, 40: 375-380.
  • 6Kilander L, Nyman H, Boberg M, et al. Hypertension is Related to Cognitive Impairment, A 20 year follow up of 999 Men[J]. Hypertension,1998,31:780-786.
  • 7Van BoxteI MP, Gaillard C, Houx PJ, et al. Is nondipping in 24 h ambulatory blood pressure related to cognitive dysfunction[J]. J Hypertens, 1998,16 : 1425-1432.
  • 8Johnston SC, O'Meara ES, ManolioTA, et al. Cognitive impair ment and decline are associated with carotid artery disease in pa tientswithout elinieally evident cerebrovascular disease[J]. Ann Intern Med,2004,140:237-247.
  • 9Pettigrew LC, Thomas N, Howard VJ, et al. Low mini-mental status predicts mortality in asymptomatic carotid arterial stenosis [J]. Neurology,2000,55:30-34.
  • 10Barnes DE, Alexopoulos GS, Lopez OL,et al. Depressive symptoms, vascular disease, and mild cognitive impairment: findings from the Cardiovascular Health Study[J]. Arch Gen Psychiatry, 2006,63:273-279.

共引文献29

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部